Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.53 |
| ▸ | PER2 | O15055 | 2/20 | 0.46 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1240227 | 0.79 | HCRTR2 (0.60) | PER2CRY2SMN1; SMN2 | |
| SCHEMBL16759677 | 0.74 | ALDH1A1 (0.65) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL20118192 | 0.74 | P2RX7 (0.45) | P2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL27091876 | 0.73 | HCRTR2 (0.58) | PER2CRY2ALDH1A1MAPT | |
| SCHEMBL2338116 | 0.72 | HCRTR1 (0.53) | PER2ALDH1A1 | |
| SCHEMBL26099354 | 0.71 | ALDH1A1 (0.54) | PER2ALDH1A1 | |
| SCHEMBL2795054 | 0.70 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL20118124 | 0.70 | P2RX7 (0.44) | P2RX7ALDH1A1 | |
| SCHEMBL20118173 | 0.70 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL24769847 | 0.69 | P2RX7 (0.57) | P2RX7ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |