Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24703987 | 0.82 | PTGS2 (0.44) | PTGS2ALDH1A1GAATUBB1HTR2A | |
| SCHEMBL24703587 | 0.81 | SRC (0.43) | PTGS2ALDH1A1GAATUBB1HTR2A | |
| SCHEMBL30374 | 0.81 | PTGS2 (1.00) | PTGS2TUBB1HTR2AHTR2CHTR2B | |
| SCHEMBL1968791 | 0.79 | HTR2A (0.70) | PTGS2GAATUBB1HTR2AHTR2C | |
| SCHEMBL31540294 | 0.78 | PTGS2 (0.69) | PTGS2TUBB1HTR2AHTR2CHTR2B | |
| SCHEMBL14190879 | 0.77 | CA2 (0.52) | PTGS2ALDH1A1GAA | |
| SCHEMBL8372213 | 0.77 | CA2 (0.52) | PTGS2ALDH1A1 | |
| SCHEMBL17051334 | 0.75 | PTGS2 (0.65) | PTGS2TUBB1HTR2AHTR2CHTR2B | |
| SCHEMBL4114610 | 0.75 | GAA (0.42) | PTGS2ALDH1A1GAAHTR2AHTR2C | |
| SCHEMBL18071824 | 0.75 | PTGS2 (0.72) | PTGS2TUBB1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |