Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 1.00 |
| ▸ | CA2 | P00918 | 13/20 | 1.00 |
| ▸ | CA9 | Q16790 | 13/20 | 1.00 |
| ▸ | CA12 | O43570 | 11/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299104 | 0.92 | CA1 (0.86) | CA1CA2CA9CA12LMNA | |
| SCHEMBL12793541 | 0.83 | CA12 (0.71) | CA1CA2CA9CA12LMNA | |
| SCHEMBL481254 | 0.80 | CA12 (0.67) | CA1CA2CA9CA12LMNA | |
| SCHEMBL11478927 | 0.80 | CA12 (0.67) | CA1CA2CA9CA12LMNA | |
| SCHEMBL1632277 | 0.78 | CA1 (0.63) | CA1CA2CA9CA12SCN2A | |
| SCHEMBL1957622 | 0.76 | CA2 (0.76) | CA1CA2CA9CA12SCN2A | |
| SCHEMBL12793823 | 0.76 | ALDH1A1 (0.68) | CA1CA2CA9CA12LMNA | |
| SCHEMBL11644411 | 0.74 | CA1 (0.74) | CA1CA2CA9CA12SCN2A | |
| SCHEMBL18118186 | 0.74 | AKR1C3 (0.65) | CA1CA2CA9CA12LMNA | |
| SCHEMBL22693763 | 0.74 | CA1 (0.58) | CA1CA2CA9CA12SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118857-A1 | PROCESS FOR FUNCTIONALISING POLYMERS | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-05-03 | — | — | US | disclosed |