Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21583190 | 0.81 | F11 (0.39) | F11FFAR1 | |
| SCHEMBL18567823 | 0.80 | LPL (0.39) | P4HB | |
| SCHEMBL18567448 | 0.80 | LIPG (0.41) | F11P4HB | |
| SCHEMBL15400281 | 0.74 | FFAR1 (0.36) | F11FFAR1P4HB | |
| SCHEMBL1302760 | 0.74 | MKNK1 (0.39) | F11FFAR1P4HB | |
| SCHEMBL16872278 | 0.74 | HCAR2 (0.47) | F11FFAR1P4HB | |
| SCHEMBL12373176 | 0.74 | LPL (0.44) | F11FFAR1 | |
| SCHEMBL1052988 | 0.73 | ATM (0.51) | F11P4HB | |
| SCHEMBL30121332 | 0.73 | ATM (0.51) | F11P4HB | |
| SCHEMBL29588576 | 0.73 | F11 (0.40) | F11FFAR1P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2908824-B1 | TRICYCLIC SUBSTITUTED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME (US) | 2018-05-02 | — | — | EP | disclosed |