SCHEMBL20119693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20119459	0.83	RECQL (0.51)	RECQLSMN1; SMN2TMIGD3HTR2CHTR2B
	SCHEMBL20119583	0.83	TMIGD3 (0.43)	SMN1; SMN2TMIGD3HTR2CHTR2BCDK2
	SCHEMBL15950875	0.81	RECQL (0.45)	KCNH3RECQLSMN1; SMN2CDK2JAK2
	SCHEMBL20119917	0.81	MAP4K4 (0.38)	RECQLSMN1; SMN2TMIGD3HTR2CHTR2B
	SCHEMBL20119640	0.80	KCNH3 (0.40)	KCNH3CDK2CCNE1JAK2IGF1R
	SCHEMBL20119909	0.79	CDK2 (0.39)	KCNH3RECQLSMN1; SMN2TMIGD3HTR2C
	SCHEMBL20119597	0.79	LMNA (0.38)	SMN1; SMN2TMIGD3HTR2CHTR2BCDK2
	SCHEMBL25873886	0.78	KCNH3 (0.37)	KCNH3CDK2CCNE1JAK2IGF1R
	SCHEMBL20119926	0.78	KCNH3 (0.37)	KCNH3CDK2CCNE1JAK2IGF1R
	SCHEMBL20119892	0.78	KCNH3 (0.43)	KCNH3SMN1; SMN2CDK2CCNE1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.