Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509793 | 0.88 | TP53 (0.53) | CDK2TP53MAPTALDH1A1NPSR1 | |
| SCHEMBL15322731 | 0.85 | SPR (0.47) | CDK2TP53ALDH1A1NPSR1KDM4E | |
| SCHEMBL14564407 | 0.85 | MAPT (0.50) | CDK2MAPTALDH1A1KMOKDM4E | |
| SCHEMBL23226415 | 0.84 | MCL1 (0.53) | CDK2KMOPLA2G4AKMT2AMEN1 | |
| SCHEMBL19872707 | 0.84 | HPGD (0.48) | CDK2TP53ALDH1A1NPSR1KDM4E | |
| SCHEMBL20935020 | 0.84 | CDK2 (0.52) | CDK2TP53ALDH1A1NPSR1KDM4E | |
| SCHEMBL23226315 | 0.83 | KMT2A (0.42) | CDK2TP53ALDH1A1NPSR1KDM4E | |
| SCHEMBL20120024 | 0.82 | PTGER1 (0.49) | TP53KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL19872723 | 0.82 | POLB (0.56) | ALDH1A1KMOPOLBPLA2G4AKMT2A | |
| SCHEMBL18509259 | 0.81 | TRPM5 (0.41) | CDK2TP53ALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |