Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509430 | 0.89 | NR4A2 (0.55) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL18509447 | 0.88 | NR4A2 (0.47) | NR4A2RXRARXRBFFAR4 | |
| SCHEMBL21614274 | 0.85 | HTR2A (0.45) | KMT2AMEN1NR4A2RXRARXRB | |
| SCHEMBL1326755 | 0.83 | CMA1 (0.63) | KMT2AMEN1CMA1TP53KDM4E | |
| SCHEMBL15322731 | 0.82 | SPR (0.47) | KMT2AMEN1CMA1TP53KDM4E | |
| SCHEMBL20119861 | 0.82 | CDK2 (0.51) | KMT2AMEN1CMA1TP53KDM4E | |
| SCHEMBL23226415 | 0.81 | MCL1 (0.53) | KMT2AMEN1CMA1GPR17 | |
| SCHEMBL20935020 | 0.81 | CDK2 (0.52) | KMT2AMEN1CMA1TP53KDM4E | |
| SCHEMBL19872707 | 0.81 | HPGD (0.48) | KMT2AMEN1CMA1TP53KDM4E | |
| SCHEMBL23226315 | 0.80 | KMT2A (0.42) | KMT2AMEN1CMA1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183358-A2 | WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |