Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20935033 | 0.90 | NR4A2 (0.56) | NR4A2NR1D1CCNCCDK8ALDH1A1 | |
| SCHEMBL20120024 | 0.88 | PTGER1 (0.49) | NR4A2FFAR4RXRARXRB | |
| SCHEMBL24143036 | 0.82 | HTR2A (0.54) | NR4A2NR1D1CHEK1CCNCCDK8 | |
| SCHEMBL21392031 | 0.81 | NR4A2 (0.49) | NR4A2NR1D1HDAC8CHEK1CAPN1 | |
| SCHEMBL19871248 | 0.80 | ALDH1A1 (0.46) | NR4A2NR1D1HDAC8CHEK1CAPN1 | |
| SCHEMBL24143779 | 0.80 | NR1D1 (0.50) | NR4A2NR1D1HDAC8CHEK1METAP2 | |
| SCHEMBL15322731 | 0.79 | SPR (0.47) | ALDH1A1MCL1 | |
| SCHEMBL20119861 | 0.79 | CDK2 (0.51) | ALDH1A1MAPTMCL1 | |
| SCHEMBL18509430 | 0.78 | NR4A2 (0.55) | NR4A2RXRARXRB | |
| SCHEMBL20935020 | 0.78 | CDK2 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229090-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | US | disclosed |
| US-20230287466-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH (US) | 2023-09-14 | — | — | US | disclosed |
| US-11591627-B2 | Modified bacteria for production of nitroaromatics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210108237-A1 | WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-04-15 | — | — | US | disclosed |
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | CYP4F2, CYP2F1, POR | NR4A2 2093/4885NR1D1 751/4885HDAC8 4088/4885 |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, CYP2F1, POR | NR4A2 2093/4885NR1D1 751/4885HDAC8 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.