Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.46 |
| ▸ | CHRNG | P07510 | 2/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | CHRND | Q07001 | 2/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464546 | 0.85 | KMT2A (0.39) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL27871195 | 0.80 | PARP1 (0.47) | HTTKDM4EPARP1SLC6A2SLC6A3 | |
| SCHEMBL8081217 | 0.78 | PARP1 (0.48) | PARP1SLC6A2SLC6A3CHRNA1CHRNG | |
| SCHEMBL1361076 | 0.77 | PARP1 (0.52) | HTTKDM4EPARP1SLC6A2SLC6A3 | |
| SCHEMBL1794480 | 0.76 | PARP1 (0.56) | HTTKDM4EPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20148791 | 0.76 | CES2 (0.50) | PARP1SLC6A2SLC6A3CHRNB2CHRNB4 | |
| SCHEMBL18785491 | 0.76 | LMNA (0.33) | SMN1; SMN2GAAMAPT | |
| SCHEMBL8159886 | 0.76 | SLC6A2 (0.63) | HTTKDM4EPARP1SLC6A2SLC6A3 | |
| SCHEMBL9686798 | 0.74 | SLC6A2 (0.48) | HTTKDM4EPARP1SLC6A2SLC6A3 | |
| SCHEMBL10305470 | 0.74 | SLC6A2 (0.61) | HTTPARP1SLC6A2SLC6A3CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090006-A1 | METHODS FOR DRUG DISCOVERY USING STEM CELL-DERIVED SCHWANN CELLS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2018-05-17 | — | — | WO | disclosed |
| CN-102652159-B | Stain-resistant aqueous coating composition | AKZO NOBEL COATINGS INT BV | 2014-08-13 | — | — | CN | disclosed |
| EP-2513237-B1 | STAIN-BLOCKING AQUEOUS COATING COMPOSITION | AKZO NOBEL COATINGS INT BV (NL) | 2014-06-18 | — | — | EP | disclosed |
| US-8709609-B2 | Stain-blocking aqueous coating composition | AKZO NOVEL COATINGS INTERNATIONAL B.V. (NL) | 2014-04-29 | — | — | US | disclosed |
| EP-2513237-A1 | STAIN-BLOCKING AQUEOUS COATING COMPOSITION | Akzo Nobel Coatings International B.V. (NL) | 2012-10-24 | — | — | EP | disclosed |
| US-20120244368-A1 | STAIN-BLOCKING AQUEOUS COATING COMPOSITION | AKZO NOBEL COATING INTERNATIONAL B.V. (NL) | 2012-09-27 | — | — | US | disclosed |
| CN-102652159-A | Stain-resistant aqueous coating composition | AKZO NOBEL COATINGS INT BV | 2012-08-29 | — | — | CN | disclosed |
| WO-2011073164-A1 | STAIN-BLOCKING AQUEOUS COATING COMPOSITION | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2011-06-23 | — | — | WO | disclosed |
| EP-0197274-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED STYRENES | BAYER AG (DE) | 1989-01-04 | — | — | EP | disclosed |
| US-4650910-A | CLEAVAGE OF N-ACYL-B-PHENETHYLAMINES WITH BASE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-17 | — | — | US | disclosed |
| EP-0197274-A1 | Process for the preparation of substituted styrenes | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |