SCHEMBL9686798

SCHEMBL9686798

CC(C)C(=C(Cl)Cl)c1cccc(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.48
SLC6A3 Q01959 4/20 0.48
PARP1 P09874 1/20 0.46
HPGD P15428 2/20 0.45
CHRNA1 P02708 2/20 0.45
CHRNG P07510 2/20 0.45
CHRNB1 P11230 2/20 0.45
CHRNB2 P17787 2/20 0.45
CHRNB4 P30926 2/20 0.45
SLC6A4 P31645 2/20 0.45
CHRNA3 P32297 2/20 0.45
CHRNA4 P43681 2/20 0.45
CHRND Q07001 2/20 0.45
ITGA5 P08648 1/20 0.45
CYP2C19 P33261 1/20 0.45
HRH1 P35367 1/20 0.45
CHRNA7 P36544 1/20 0.45
OPRK1 P41145 1/20 0.45
KCNH2 Q12809 1/20 0.45
ALDH1A1 P00352 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249689 0.81 PARP1 (0.46) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL9687337 0.81 CA12 (0.44) PARP1ALDH1A1KDM4EGAAMAPT
SCHEMBL8159886 0.74 SLC6A2 (0.63) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL2012003 0.74 HTT (0.47) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL14511436 0.72 PARP1 (0.53) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL3096979 0.70 PARP1 (0.56) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL4375606 0.70 PARP1 (0.56) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL8568759 0.69 PARP1 (0.50) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL8568764 0.69 PARP1 (0.50) SLC6A2SLC6A3PARP1HPGDCHRNA1
SCHEMBL4088684 0.69 PARP1 (0.60) PARP1HPGDALDH1A1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136114-A PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed