Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644039 | 0.83 | GAA (0.61) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL880823 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL30525199 | 0.78 | RAPGEF4 (0.56) | ALDH1A1LMNAMAPTGAAMEN1 | |
| SCHEMBL11406554 | 0.78 | RAPGEF4 (0.56) | ALDH1A1LMNAMAPTGAAMEN1 | |
| SCHEMBL20612556 | 0.76 | CYP3A4 (0.71) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL7003942 | 0.76 | RAPGEF4 (0.64) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL4830911 | 0.76 | MAPT (0.49) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL30991860 | 0.76 | CYP3A4 (0.71) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL6757211 | 0.75 | CXCR1 (0.43) | KDM4EALDH1A1LMNAMAPTALOX15 | |
| SCHEMBL11421284 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |