SCHEMBL2012048

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2007089	0.93	ALDH1A1 (0.42)	HSD11B1ACHECNR1ALDH1A1GAA
	SCHEMBL2006369	0.92	HSD11B1 (0.50)	HSD11B1MAPTRECQLACHEPOLB
	SCHEMBL3054414	0.90	ALDH1A1 (0.40)	HSD11B1ACHECNR1ALDH1A1GAA
	SCHEMBL3052047	0.89	ALDH1A1 (0.40)	HSD11B1ACHECNR1ALDH1A1GAA
	SCHEMBL4685416	0.89	HSD11B1 (0.41)	HSD11B1MAPTRECQL
	SCHEMBL4685105	0.88	HSD11B1 (0.43)	HSD11B1CNR1ALDH1A1GAATSHR
	SCHEMBL2007974	0.88	HSD11B1 (0.43)	HSD11B1CNR1ALDH1A1GAATSHR
	SCHEMBL2010440	0.88	PSEN1 (0.42)	HSD11B1ACHECNR1ALDH1A1GAA
	SCHEMBL12569122	0.88	HSD11B1 (0.45)	HSD11B1ACHECNR1ALDH1A1GAA
	SCHEMBL13270904	0.88	ALDH1A1 (0.39)	HSD11B1ACHECNR1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.