Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1546076 | 0.90 | EPAS1 (0.36) | ALDH1A1EPAS1 | |
| SCHEMBL943033 | 0.87 | EPAS1 (0.33) | ALDH1A1EPAS1 | |
| SCHEMBL17733612 | 0.85 | EPAS1 (0.32) | ALDH1A1EPAS1 | |
| SCHEMBL10149928 | 0.85 | EPAS1 (0.32) | ALDH1A1EPAS1 | |
| SCHEMBL5680966 | 0.83 | EPAS1 (0.35) | SMN1; SMN2EPAS1 | |
| SCHEMBL20256032 | 0.83 | EPAS1 (0.35) | ALDH1A1EPAS1 | |
| SCHEMBL2078709 | 0.83 | EPHX1 (0.33) | CXCR4SMN1; SMN2ALDH1A1EPAS1 | |
| SCHEMBL6512104 | 0.83 | HTR2C (0.35) | — | |
| SCHEMBL10594 | 0.83 | EPAS1 (0.33) | SMN1; SMN2EPAS1 | |
| SCHEMBL433801 | 0.81 | SLC6A1 (0.34) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963435-B2 | Compounds for therapeutic use | DART NEUROSCIENCE, LLC (US) | 2018-05-08 | — | — | US | disclosed |