Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122036 | 0.88 | EPHX2 (0.39) | EPHX2KDM1AFFAR1FFAR4 | |
| SCHEMBL17911600 | 0.71 | EPHX2 (0.57) | EPHX2FFAR1GSK3AGSK3BFFAR4 | |
| SCHEMBL20122021 | 0.70 | EPHX2 (0.50) | EPHX2GSK3AGSK3B | |
| SCHEMBL17916347 | 0.67 | EPHX2 (0.44) | EPHX2KDM1AGSK3AGSK3BRXRA | |
| SCHEMBL5652618 | 0.67 | FFAR1 (0.63) | FFAR1FFAR4NR1H4ALDH1A1 | |
| SCHEMBL4883797 | 0.64 | FFAR1 (0.54) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL17911590 | 0.63 | EPHX2 (0.52) | EPHX2FFAR1GSK3AGSK3BFFAR4 | |
| SCHEMBL9425104 | 0.63 | FFAR1 (0.69) | FFAR1FFAR4 | |
| SCHEMBL20122035 | 0.62 | EPHX2 (0.47) | EPHX2FFAR1GSK3AGSK3B | |
| SCHEMBL8972254 | 0.61 | NR1H4 (0.51) | EPHX2FFAR1FFAR4NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963439-B2 | Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-05-08 | — | — | US | disclosed |