SCHEMBL4883797

SCHEMBL4883797

Cc1ccc(Nc2ccc(CCC(=O)O)cc2)cc1C

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 16/20 0.54
ALDH1A1 P00352 1/20 0.49
FFAR4 Q5NUL3 3/20 0.49
POLB P06746 1/20 0.47
DGAT1 O75907 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289443 0.85 SMN1; SMN2 (0.49) ALDH1A1POLB
SCHEMBL5652618 0.85 FFAR1 (0.63) FFAR1ALDH1A1FFAR4
SCHEMBL585013 0.81 FFAR4 (0.58) FFAR1ALDH1A1FFAR4
SCHEMBL391961 0.80 FFAR1 (0.47) FFAR1POLB
SCHEMBL9425104 0.80 FFAR1 (0.69) FFAR1FFAR4
SCHEMBL7761596 0.80 EPHX2 (0.49) ALDH1A1POLB
SCHEMBL394462 0.78 ALDH1A1 (0.54) ALDH1A1POLB
SCHEMBL25445848 0.76 MAPT (0.43) ALDH1A1POLB
SCHEMBL3919619 0.76 HPGD (0.48) ALDH1A1POLB
SCHEMBL1921405 0.75 GAA (0.52) ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080057424-A1 Overcoat for electrophotographic imaging member and methods of making and using same XEROX CORPORATION 2008-03-06 US disclosed