Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 15/20 | 0.42 |
| ▸ | RXRB | P28702 | 15/20 | 0.42 |
| ▸ | RXRG | P48443 | 13/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17916279 | 0.91 | CYP26A1 (0.46) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL17916345 | 0.82 | CYP26A1 (0.46) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL20122034 | 0.72 | CYP26A1 (0.36) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL17914352 | 0.69 | RXRA (0.54) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL24259952 | 0.68 | CYP26A1 (0.64) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL6147014 | 0.68 | RXRA (0.46) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL6147306 | 0.68 | RXRA (0.46) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL20277839 | 0.68 | RXRA (0.53) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL6528854 | 0.68 | RXRA (0.53) | CYP26A1RXRARXRBRXRGRARB | |
| SCHEMBL6146944 | 0.66 | RXRA (0.53) | CYP26A1RXRARXRBRXRGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963439-B2 | Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-05-08 | — | — | US | disclosed |