Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | GAA | P10253 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MPI | P34949 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | G6PD | P11413 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680120 | 0.87 | MAPT (0.76) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3854531 | 0.84 | MAPT (1.00) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL22585319 | 0.84 | MAPT (0.72) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL13680051 | 0.84 | MAPT (1.00) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3854527 | 0.84 | MAPT (1.00) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL13680121 | 0.83 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3858944 | 0.82 | MAPT (0.70) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL13679925 | 0.82 | MAPT (0.70) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL3858947 | 0.82 | MAPT (0.70) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL20122064 | 0.82 | MAPT (0.78) | ALDH1A1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220442-A1 | Random Heteropolymers Preserve Protein Function in Foreign Environments | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230220442-A1 | Random Heteropolymers Preserve Protein Function in Foreign Environments | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-13 | — | — | US | disclosed |
| US-11597845-B2 | Coating for aldehyde remediation and method of making | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-03-07 | — | — | US | disclosed |
| US-20210275997-A9 | MAGNETIC MACROPOROUS POLYMERIC HYBRID SCAFFOLDS FOR IMMOBILIZING BIONANOCATALYSTS | ZYMTRONIX CATALYTIC SYSTEMS, INC. (US) | 2021-09-09 | — | — | US | disclosed |
| US-20200330967-A1 | MAGNETIC MACROPOROUS POLYMERIC HYBRID SCAFFOLDS FOR IMMOBILIZING BIONANOCATALYSTS | ZYMTRONIX CATALYTIC SYSTEMS, INC. (US) | 2020-10-22 | — | — | US | disclosed |
| US-20200318154-A1 | Random Heteropolymers Preserve Protein Function in Foreign Environments | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-10-08 | — | — | US | disclosed |
| US-20200165463-A1 | COATING FOR ALDEHYDE REMEDIATION AND METHOD OF MAKING | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2020-05-28 | — | — | US | disclosed |
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |
| US-20090044348-A1 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-02-19 | — | — | US | disclosed |
| US-20090044348-A1 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-02-19 | — | — | US | disclosed |
| US-20090044348-A1 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-02-19 | — | — | US | disclosed |
| EP-2011787-A1 | Dying composition comprising an azomethin-type compound with a pyrazolinone moiety | L'Oreal (FR) | 2009-01-07 | — | — | EP | disclosed |
| US-20070196861-A1 | METHOD FOR FORMING FILM, BASE PLATE WITH FILM, SENSOR, AND LIQUID COMPOSITION | SEIKO EPSON CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070196861-A1 | METHOD FOR FORMING FILM, BASE PLATE WITH FILM, SENSOR, AND LIQUID COMPOSITION | SEIKO EPSON CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| US-6989254-B2 | Direct encapsulation of biomacromolecules in surfactant templated mesoporous and nanoporous materials | DREXEL UNIVERSITY (US) | 2006-01-24 | — | — | US | disclosed |
| US-20040014189-A1 | Direct encapsulation of biomacromolecules in surfactant templated mesoporous and nanoporous materials | DREXEL UNIVERSITY | 2004-01-22 | — | — | US | disclosed |
| WO-2002010218-A1 | DIRECT ENCAPSULATION OF BIOMACROMOLECULES IN SURFACTANT TEMPLATED MESOPOROUS AND NANOPOROUS MATERIALS | DREXEL UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090044348-A1 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | KRT18, KMO, TMPO | ALDH1A1 729/4885MAPT 308/4885GAA 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.