Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15304182 | 0.82 | ALDH1A1 (0.36) | GRNSORT1IDO1ALDH1A1HTT | |
| SCHEMBL24919732 | 0.82 | ALDH1A1 (0.36) | GRNSORT1IDO1ALDH1A1HTT | |
| SCHEMBL26928487 | 0.80 | GRN (0.36) | GRNSORT1IDO1ALDH1A1HTT | |
| SCHEMBL3727796 | 0.80 | TAAR1 (0.42) | GRNSORT1IDO1ALDH1A1HTT | |
| SCHEMBL22601334 | 0.78 | ACHE (0.33) | GRNSORT1IDO1ALDH1A1HTT | |
| SCHEMBL19943624 | 0.78 | KIT (0.37) | ALDH1A1HTTL3MBTL1 | |
| SCHEMBL22838143 | 0.77 | TAAR1 (0.44) | GRNSORT1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL19458721 | 0.77 | — | — | |
| SCHEMBL179280 | 0.76 | — | — | |
| SCHEMBL12303949 | 0.76 | EP300 (0.34) | GRNSORT1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |