Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011408 | 0.89 | HCRTR1 (0.43) | EPHX2HTR1AHTR2AHTR2CDRD3 | |
| SCHEMBL6919106 | 0.89 | HCRTR1 (0.43) | EPHX2HTR1AHTR2AHTR2CDRD3 | |
| SCHEMBL2017304 | 0.89 | HCRTR1 (0.43) | EPHX2HTR1AHTR2AHTR2CDRD3 | |
| SCHEMBL2016502 | 0.86 | HCRTR1 (0.49) | HTR1AHTR2AHTR2CDRD3HCRTR1 | |
| SCHEMBL13138994 | 0.84 | KMT2A (0.55) | EPHX2HCRTR1HCRTR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13138970 | 0.84 | KMT2A (0.55) | EPHX2HCRTR1HCRTR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13138974 | 0.84 | KMT2A (0.59) | EPHX2HCRTR1HCRTR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2014058 | 0.84 | HCRTR1 (0.62) | HTR1AHTR2AHTR2CDRD3HCRTR1 | |
| SCHEMBL13138991 | 0.84 | HCRTR1 (0.60) | EPHX2HTR1AHTR2ADRD3HCRTR1 | |
| SCHEMBL13138969 | 0.83 | HCRTR1 (0.53) | EPHX2HTR1AHTR2ADRD3HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | claimed |
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |