Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013880 | 0.96 | HCRTR1 (0.46) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2012798 | 0.93 | HCRTR1 (0.48) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2013858 | 0.90 | HCRTR1 (0.46) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2014697 | 0.90 | HCRTR1 (0.46) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2012216 | 0.86 | EPHX2 (0.47) | HCRTR1HCRTR2KLKB1HTR1AALDH1A1 | |
| SCHEMBL6919106 | 0.85 | HCRTR1 (0.43) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2017304 | 0.85 | HCRTR1 (0.43) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2011408 | 0.85 | HCRTR1 (0.43) | HCRTR1HCRTR2KLKB1CTSASIGMAR1 | |
| SCHEMBL2053123 | 0.83 | KMT2A (0.40) | HCRTR1HCRTR2KLKB1CTSAALDH1A1 | |
| SCHEMBL2013932 | 0.83 | KMT2A (0.40) | HCRTR1HCRTR2KLKB1CTSAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |