Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122296 | 0.89 | HDAC1 (0.49) | CAPN1TDP1ATMCTSKKLK7 | |
| SCHEMBL19436302 | 0.89 | TDP1 (0.44) | CAPN1ITGB3ITGA2BTDP1ATM | |
| SCHEMBL3728193 | 0.87 | CAPN1 (0.46) | CAPN1ITGB3ITGA2BTDP1ATM | |
| SCHEMBL3728197 | 0.87 | CAPN1 (0.46) | CAPN1ITGB3ITGA2BTDP1ATM | |
| SCHEMBL1904291 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BCTSKCTSSHDAC1 | |
| SCHEMBL8823986 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BCTSKCTSSHDAC1 | |
| SCHEMBL2324580 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BCTSKCTSSHDAC1 | |
| SCHEMBL20122337 | 0.85 | CAPN1 (0.54) | CAPN1TDP1ATMCTSKCTSS | |
| SCHEMBL13997312 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BTDP1ATMCTSK | |
| SCHEMBL17445167 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BTDP1ATMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3584255-B1 | MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP | SUTRO BIOPHARMA INC (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-2890402-B1 | MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP | SUTRO BIOPHARMA INC (US) | 2019-04-17 | — | — | EP | disclosed |