Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122513 | 0.83 | — | — | |
| SCHEMBL20122503 | 0.83 | — | — | |
| SCHEMBL20122458 | 0.83 | ACE (0.47) | ACEFOLH1MMEACE2 | |
| SCHEMBL20122457 | 0.83 | ACE (0.46) | ACEFOLH1MMEACE2 | |
| SCHEMBL20122501 | 0.82 | — | — | |
| SCHEMBL20122384 | 0.81 | — | — | |
| SCHEMBL11333699 | 0.78 | PPARG (0.33) | ACEMMEACE2 | |
| SCHEMBL11337774 | 0.78 | CPB2 (0.36) | ACEGRNSORT1ALDH1A1MME | |
| SCHEMBL9623845 | 0.77 | ACE (0.42) | ACEFOLH1NAALAD2ALDH1A1 | |
| SCHEMBL12308077 | 0.77 | ALDH1A1 (0.53) | ACEFOLH1NAALAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |