Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122512 | 0.93 | MAPT (0.34) | MAPTADAM17KMT2AATMALDH1A1 | |
| SCHEMBL20122510 | 0.90 | HPGD (0.40) | MAPTADAM17KMT2AATMALDH1A1 | |
| SCHEMBL20122473 | 0.86 | MAPT (0.46) | MAPTADAM17KMT2AATMALDH1A1 | |
| SCHEMBL20122446 | 0.81 | — | — | |
| SCHEMBL20122403 | 0.81 | CHRM1 (0.32) | MAPTADAM17KMT2AATMTSHR | |
| SCHEMBL20122508 | 0.80 | — | — | |
| SCHEMBL20122454 | 0.79 | MAPT (0.45) | MAPTADAM17KMT2AATMALDH1A1 | |
| SCHEMBL20122504 | 0.76 | CPB2 (0.30) | — | |
| SCHEMBL20122531 | 0.76 | KMT2A (0.38) | MAPTADAM17KMT2AATMALDH1A1 | |
| SCHEMBL20122402 | 0.75 | ATM (0.36) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963428-B1 | Bucillamine prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2018-05-08 | — | — | US | disclosed |