Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19192229 | 0.85 | RXRA (0.30) | — | |
| SCHEMBL19190921 | 0.85 | — | — | |
| SCHEMBL29404221 | 0.79 | TDP1 (0.44) | GABRA1GABRB1LMNACA1CA2 | |
| SCHEMBL1189830 | 0.79 | TDP1 (0.44) | GABRA1GABRB1LMNACA1CA2 | |
| SCHEMBL16454720 | 0.77 | GABRA1 (0.37) | GABRA1GABRB1LMNACA1CA2 | |
| SCHEMBL24032649 | 0.76 | GABRA1 (0.35) | GABRA1GABRB1LMNA | |
| SCHEMBL3268711 | 0.76 | TDP1 (0.37) | GABRA1GABRB1LMNA | |
| SCHEMBL13636034 | 0.74 | NOS3 (0.34) | LMNACA1CA2 | |
| SCHEMBL12796017 | 0.74 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL17816235 | 0.72 | GABRA1 (0.33) | GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |