SCHEMBL20123197

SCHEMBL20123197

CCCN(CC)CCOC(=O)c1csc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 4/20 0.49
SCN2A Q99250 4/20 0.49
SCN3A Q9NY46 4/20 0.49
PMM2 O15305 1/20 0.47
MPI P34949 1/20 0.47
PHOSPHO1 Q8TCT1 1/20 0.47
CHRM2 P08172 2/20 0.46
CHRM3 P20309 2/20 0.46
CHRM1 P11229 1/20 0.46
BCHE P06276 1/20 0.44
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP2D6 P10635 3/20 0.42
CYP1A2 P05177 3/20 0.42
MAOA P21397 2/20 0.42
HTR3A P46098 2/20 0.42
HRH3 Q9Y5N1 2/20 0.42
HTR2C P28335 1/20 0.42
CHRNA4 P43681 1/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20061727 0.95 SCN1A (0.45) SCN1ASCN2ASCN3APMM2MPI
SCHEMBL11814952 0.81 HDAC3 (0.56) ALDH1A1KDM4ECYP2D6CYP1A2HDAC3
SCHEMBL13610220 0.80 ALDH1A1 (0.64) ALDH1A1KDM4ECYP1A2HDAC3HDAC4
SCHEMBL9494725 0.79 TSHR (0.58) MPIPHOSPHO1ALDH1A1KDM4ECYP1A2
SCHEMBL31182024 0.73 RAB9A (0.56) ALDH1A1KDM4EHDAC3HDAC4HDAC1
SCHEMBL4765620 0.72 HDAC3 (0.43) ALDH1A1CYP2D6CYP1A2HDAC3HDAC4
SCHEMBL71339 0.71 HDAC3 (0.62) ALDH1A1KDM4ECYP1A2HDAC3HDAC4
SCHEMBL25029850 0.71 ALDH1A1 (0.58) ALDH1A1CYP2D6CYP1A2LMNACYP2C19
SCHEMBL392880 0.70 C5AR1 (0.53) ALDH1A1KDM4ECYP2D6CYP1A2HDAC3
SCHEMBL10383094 0.70 MAOB (0.55) MPIPHOSPHO1ALDH1A1KDM4EHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3319139-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR BATTERY, AND COMPOSITION Fujifilm Corporation (JP) 2018-05-09 EP disclosed