SCHEMBL20124005

SCHEMBL20124005

C=Cc1ccccc1OS(N)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.45
CA9 Q16790 9/20 0.45
CA1 P00915 8/20 0.45
ALDH1A1 P00352 3/20 0.43
STS P08842 4/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12490776 0.82 ALDH1A1 (0.62) CA2CA9CA1ALDH1A1STS
SCHEMBL731975 0.81 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL7787737 0.81 SMN1; SMN2 (0.44) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL29743115 0.81 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL28986963 0.79 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL9451267 0.79 CA2 (0.61) CA2CA9CA1STS
SCHEMBL9236086 0.78 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL7086093 0.77 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL7107507 0.77 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL8813181 0.77 ALDH1A1 (0.44) CA2CA9CA1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2686298-B1 SUBSTITUTED DIPHENYL DERIVATIVES CREATIVE THERAPEUTICS GMBH (DE) 2018-05-09 EP disclosed