SCHEMBL7787737

SCHEMBL7787737

C=Cc1ccccc1OS(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 5/20 0.43
NFE2L2 Q16236 6/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 2/20 0.39
MAPK1 P28482 1/20 0.39
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
PPARG P37231 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1200479 0.82 ALDH1A1 (0.62) SMN1; SMN2ALDH1A1NFE2L2MEN1KMT2A
SCHEMBL9236086 0.81 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1NFE2L2MEN1KMT2A
SCHEMBL731975 0.81 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1NFE2L2MEN1KMT2A
SCHEMBL29743115 0.81 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1NFE2L2MEN1KMT2A
SCHEMBL20124005 0.81 CA2 (0.45) ALDH1A1MEN1KMT2ALMNAMAPK1
SCHEMBL28986963 0.79 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1NFE2L2MEN1KMT2A
SCHEMBL28306652 0.79 SMN1; SMN2 (0.40) SMN1; SMN2KMT2AHTT
SCHEMBL3839152 0.79 NFE2L2 (0.42) SMN1; SMN2ALDH1A1NFE2L2KMT2A
SCHEMBL7107507 0.77 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1NFE2L2MEN1KMT2A
SCHEMBL7086093 0.77 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705503-B As the heteroaryl piperidine of fungicide and the malonic ester derivatives of heteroaryl piperazine 拜耳作物科学股份公司 2019-07-09 CN disclosed
CN-105473585-B Piperidine carboxylic acid derivative as fungicide 拜耳作物科学股份公司 2018-04-13 CN disclosed
US-9924721-B2 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-03-27 US disclosed
EP-3013821-B1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2018-03-14 EP disclosed
US-9717243-B2 Piperidinecarboxylic acid derivatives as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-01 US disclosed
US-20160198713-A1 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-07-14 US disclosed
EP-3039023-A1 MALONIC ESTER DERIVATIVES OF HETEROARYLPIPERIDINES AND -PIPERAZINES AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-07-06 EP disclosed
CN-105705503-A Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides 拜耳作物科学股份公司 2016-06-22 CN disclosed
US-20160135461-A1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-05-19 US disclosed
EP-3013821-A1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-05-04 EP disclosed
US-5077165-A Photoconductive layers of zinc oxide and hydrophilic binder resins; antistatic agents FUJI PHOTO FILM CO., LTD. (JP) 1991-12-31 US disclosed
US-5077166-A Binder of acrylic copolymers with acidic groups and polyester copolymers; photocurable; moisture resistant, durable, excellent electrostatic characteristics FUJI PHOTO FILM CO., LTD. (JP) 1991-12-31 US disclosed
EP-0459240-A1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-04 EP disclosed
EP-0456486-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1991-11-13 EP disclosed
EP-0444653-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-09-04 EP disclosed
EP-0440226-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-08-07 EP disclosed
EP-0416591-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-03-13 EP disclosed
EP-0410324-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD (JP) 1991-01-30 EP disclosed
EP-0407936-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-16 EP disclosed
EP-0405499-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160198713-A1 Malonic ester derivatives of heteroarylpiperidines and -piperazines as fungicides ME1, CYP1A1, CYP1A2 SMN1; SMN2 3695/4885ALDH1A1 383/4885NFE2L2 814/4885
US-20160135461-A1 PIPERIDINECARBOXYLIC ACID DERIVATIVES AS FUNGICIDES CYP1A1, PRXL2A, Q6ZSR9 SMN1; SMN2 3788/4885ALDH1A1 120/4885NFE2L2 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.