Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631659 | 0.85 | SMN1; SMN2 (0.49) | MAOASMN1; SMN2AHRKMT2AALDH1A1 | |
| SCHEMBL25034954 | 0.77 | SMN1; SMN2 (0.47) | MAOASMN1; SMN2AHRKMT2AALDH1A1 | |
| SCHEMBL24816077 | 0.73 | HPGD (0.44) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL31696573 | 0.73 | AHR (0.61) | MAOASMN1; SMN2AHRALDH1A1KDM4E | |
| SCHEMBL1164787 | 0.73 | AHR (0.61) | MAOASMN1; SMN2AHRALDH1A1KDM4E | |
| SCHEMBL17033994 | 0.71 | MAOA (0.45) | MAOASMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL29850525 | 0.70 | KMT2A (0.62) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL25033989 | 0.70 | SMN1; SMN2 (0.47) | MAOASMN1; SMN2AHRKMT2AALDH1A1 | |
| SCHEMBL15304530 | 0.70 | KMT2A (0.62) | SMN1; SMN2KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7427455 | 0.69 | LMNA (0.47) | MAOAALDH1A1KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-A1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2018-05-09 | — | — | EP | disclosed |