Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 4/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | MASTL | Q96GX5 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965317 | 0.91 | NOS3 (0.42) | PIM1SYKNR4A2IDH2ALDH1A1 | |
| SCHEMBL9972431 | 0.82 | KARS1 (0.45) | PIM1SYKNR4A2PIK3C3NOS3 | |
| SCHEMBL9938726 | 0.76 | SYK (0.40) | SYKIDH2ALDH1A1LMNAGLA | |
| SCHEMBL25894645 | 0.74 | SYK (0.39) | PIM1SYKIDH2ALDH1A1LMNA | |
| SCHEMBL22135115 | 0.73 | SYK (0.39) | PIM1SYKIDH2ALDH1A1LMNA | |
| SCHEMBL9965322 | 0.71 | NR4A2 (0.38) | PIM1NR4A2LMNAPIK3C3NOS3 | |
| SCHEMBL9942448 | 0.71 | LMNA (0.41) | SYKIDH2ALDH1A1LMNAGLA | |
| SCHEMBL1702136 | 0.70 | KARS1 (0.43) | SYKIDH2LMNAL3MBTL1NOS3 | |
| SCHEMBL22162991 | 0.70 | SYK (0.36) | PIM1SYKIDH2ALDH1A1LMNA | |
| SCHEMBL29498282 | 0.69 | IDH2 (0.44) | SYKIDH2MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651416-B1 | COMPOUNDS USEFUL FOR TREATING AIDS | ABIVAX (FR) | 2018-05-09 | — | — | EP | disclosed |