Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOA | P61586 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811632 | 0.79 | TOP2A (0.59) | RHOAAURKARPS6KB1NCF1NPC1 | |
| SCHEMBL7967721 | 0.76 | RHOA (0.55) | RHOAAURKARPS6KB1NCF1NPC1 | |
| SCHEMBL27960259 | 0.76 | RHOA (0.52) | RHOAAURKARPS6KB1NCF1NPC1 | |
| SCHEMBL396525 | 0.71 | NCF1 (0.61) | RHOAAURKARPS6KB1NCF1NPC1 | |
| SCHEMBL29833517 | 0.71 | NCF1 (0.61) | RHOAAURKARPS6KB1NCF1NPC1 | |
| SCHEMBL1701970 | 0.71 | NPC1 (0.61) | RHOANCF1NPC1NFKB1RAB9A | |
| SCHEMBL3951916 | 0.71 | IGF1R (0.55) | RHOANCF1NPC1NFKB1RAB9A | |
| SCHEMBL27960237 | 0.71 | NPC1 (0.58) | RHOAAURKARPS6KB1NPC1NFKB1 | |
| SCHEMBL27960312 | 0.71 | RHOA (0.42) | RHOAAURKARPS6KB1KDM4EALDH1A1 | |
| SCHEMBL27960250 | 0.70 | RHOA (0.61) | RHOAAURKARPS6KB1NPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651416-B1 | COMPOUNDS USEFUL FOR TREATING AIDS | ABIVAX (FR) | 2018-05-09 | — | — | EP | disclosed |