Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.59 |
| ▸ | RHOA | P61586 | 3/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27960259 | 0.89 | RHOA (0.52) | TOP2ATOP2BRHOAABCG2AURKA | |
| SCHEMBL7967721 | 0.83 | RHOA (0.55) | TOP2ATOP2BRHOAAURKARPS6KB1 | |
| SCHEMBL27960256 | 0.81 | RHOA (0.69) | TOP2ATOP2BRHOAABCG2ABL1 | |
| SCHEMBL27960237 | 0.79 | NPC1 (0.58) | RHOAAURKARPS6KB1KMT2ANPC1 | |
| SCHEMBL20124501 | 0.79 | RHOA (0.46) | TOP2ATOP2BRHOAAURKARPS6KB1 | |
| SCHEMBL27960250 | 0.79 | RHOA (0.61) | RHOAAURKARPS6KB1CYSLTR1KMT2A | |
| SCHEMBL396525 | 0.77 | NCF1 (0.61) | RHOAAURKARPS6KB1KMT2ANPC1 | |
| SCHEMBL29833517 | 0.77 | NCF1 (0.61) | RHOAAURKARPS6KB1KMT2ANPC1 | |
| SCHEMBL1701970 | 0.77 | NPC1 (0.61) | RHOAABCG2KMT2ANPC1NFKB1 | |
| SCHEMBL3951916 | 0.77 | IGF1R (0.55) | RHOAABCG2KMT2ANPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787992-A | N,N-double substituted benzoazacyclo-2-amide compound and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-05-14 | — | — | CN | disclosed |