Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5798391 | 0.84 | TSHR (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13097377 | 0.70 | ESR1 (0.50) | OPRM1SLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL7501445 | 0.70 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL4270075 | 0.69 | ESR1 (0.48) | OPRM1SLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL13097331 | 0.67 | ESR1 (0.50) | OPRM1SLC6A2SLC6A4SLC6A3ESR1 | |
| SCHEMBL10452118 | 0.66 | TRPA1 (0.40) | ESR1MEN1KMT2ATRPA1 | |
| SCHEMBL10452119 | 0.66 | TRPA1 (0.40) | ESR1MEN1KMT2ATRPA1 | |
| SCHEMBL10452117 | 0.66 | TRPA1 (0.40) | ESR1MEN1KMT2ATRPA1 | |
| SCHEMBL6442514 | 0.66 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1TRPA1 | |
| SCHEMBL5158078 | 0.65 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513041-A1 | PROCESS FOR THE PREPARATION OF O-DESMETHYL-VENLAFAXINE AND SALTS THEREOF | Pharmathen S.A. (GR) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072703-A1 | PROCESS FOR THE PREPARATION OF O-DESMETHYL-VENLAFAXINE AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2011-06-23 | — | — | WO | disclosed |
| EP-1232141-A1 | ETHERS OF O-DESMETHYL VENLAFAXINE | Wyeth (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038293-A1 | ETHERS OF O-DESMETHYL VENLAFAXINE | WYETH (US) | 2001-05-31 | — | — | WO | disclosed |