Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046150 | 0.80 | SIRT2 (0.31) | — | |
| SCHEMBL5037296 | 0.75 | — | — | |
| SCHEMBL12312030 | 0.72 | SLC6A3 (0.33) | — | |
| SCHEMBL12488334 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL8048828 | 0.72 | SLC6A3 (0.33) | — | |
| SCHEMBL17835271 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL17835272 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL17835268 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL1325803 | 0.71 | — | — | |
| SCHEMBL2012461 | 0.70 | OPRM1 (0.36) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028816-A1 | SUBSTITUTED 5-AMINO-1-PENTENE-3-OL DERIVATIVES | BUSCHMANN, HELMUT | 2002-04-11 | — | — | WO | disclosed |