Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 13/20 | 0.86 |
| ▸ | MMP2 | P08253 | 5/20 | 0.62 |
| ▸ | MMP13 | P45452 | 4/20 | 0.62 |
| ▸ | MMP14 | P50281 | 3/20 | 0.62 |
| ▸ | MMP7 | P09237 | 1/20 | 0.62 |
| ▸ | MMP12 | P39900 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12684680 | 0.92 | ADAMTS4 (1.00) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL1658546 | 0.92 | ADAMTS4 (1.00) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL12247612 | 0.92 | ADAMTS4 (1.00) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL1655209 | 0.86 | ADAMTS4 (0.78) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL13314510 | 0.81 | ADAMTS4 (0.80) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL3608574 | 0.81 | ADAMTS4 (0.80) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL1658625 | 0.79 | ADAMTS4 (0.76) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL3896602 | 0.79 | ADAMTS4 (0.67) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL12684636 | 0.78 | ADAMTS4 (0.73) | ADAMTS4MMP2MMP13MMP14MMP7 | |
| SCHEMBL3618624 | 0.77 | MMP2 (1.00) | ADAMTS4MMP2MMP13MMP14MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681209-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISORDERS | AQUILUS PHARMACEUTICALS INC (US) | 2018-05-09 | — | — | EP | disclosed |