Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.32 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661710 | 1.00 | IDO1 (0.40) | IDO1PNMTP2RX7HTR3EHTR3B | |
| SCHEMBL20946381 | 0.84 | IDO1 (0.40) | IDO1PNMTP2RX7HTR3EHTR3B | |
| SCHEMBL21446974 | 0.82 | IDO1 (0.39) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7932564 | 0.82 | P2RX7 (0.37) | IDO1P2RX7HTR3EHTR3BHTR3A | |
| SCHEMBL18086469 | 0.80 | P2RX7 (0.36) | IDO1P2RX7HTR3EHTR3BHTR3A | |
| SCHEMBL14911360 | 0.80 | P2RX7 (0.36) | IDO1P2RX7HTR3EHTR3BHTR3A | |
| SCHEMBL15173346 | 0.76 | TAAR1 (0.47) | IDO1PNMTP2RX7DPP4TAAR1 | |
| SCHEMBL1765193 | 0.75 | PNMT (0.48) | IDO1PNMTDPP4HTR2CHTR2B | |
| SCHEMBL269809 | 0.74 | P2RX7 (0.36) | IDO1P2RX7NOTUMKDRCLCN2 | |
| SCHEMBL18302050 | 0.74 | AKR1B1 (0.47) | P2RX7KDRCLCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | B.C.I. PHARMA (BE) | 2022-02-01 | — | — | US | disclosed |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2019-05-02 | — | — | US | disclosed |
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | ADK, TNNI3K, TNK2 | IDO1 1493/4885PNMT 1739/4885P2RX7 199/4885 |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ADK, TNNI3K, TNK2 | IDO1 1493/4885PNMT 1739/4885P2RX7 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.