Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385885 | 0.86 | CA12 (0.45) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL19385886 | 0.86 | CA12 (0.45) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL11446013 | 0.77 | PTGS2 (0.45) | ALDH1A1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL29131269 | 0.75 | LMNA (0.44) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL28628216 | 0.75 | ALDH1A1 (0.49) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL19385941 | 0.73 | KMT2A (0.44) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL19403436 | 0.73 | KMT2A (0.44) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL1537276 | 0.73 | KMT2A (0.44) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL4953295 | 0.72 | CA12 (0.52) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL490286 | 0.72 | ALDH1A1 (0.50) | CA12CA7CA9CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |