Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550642 | 0.84 | LMNA (0.43) | LMNAALDH1A1RAB9AS1PR4TP53 | |
| SCHEMBL15786414 | 0.75 | RAB9A (0.44) | PTGS2L3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL31185803 | 0.74 | PTGS2 (0.73) | PTGS2ALDH1A1CNR1CNR2GPR84 | |
| SCHEMBL18586439 | 0.74 | PTGS2 (0.73) | PTGS2ALDH1A1CNR1CNR2GPR84 | |
| SCHEMBL31185907 | 0.74 | PTGS2 (0.73) | PTGS2ALDH1A1CNR1CNR2GPR84 | |
| SCHEMBL31185832 | 0.74 | PTGS2 (0.73) | PTGS2ALDH1A1CNR1CNR2GPR84 | |
| SCHEMBL1633455 | 0.73 | LMNA (0.43) | PTGS2LMNAALDH1A1RAB9AS1PR4 | |
| SCHEMBL1171756 | 0.72 | PTGS2 (0.76) | PTGS2ALDH1A1CNR1CNR2GPR84 | |
| SCHEMBL8229999 | 0.72 | PTGS2 (0.65) | PTGS2CNR1CNR2GPR84FUT7 | |
| SCHEMBL15783494 | 0.70 | NOTUM (0.42) | PTGS2LMNAALDH1A1RAB9AS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970275-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2018-05-09 | — | — | EP | disclosed |