Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.36 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19751550 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL19737442 | 0.82 | ADRA2A (0.41) | ALDH1A1GAAMAPTHSD17B10FABP6 | |
| SCHEMBL19737593 | 0.81 | MAPT (0.36) | ALDH1A1GAAMAPTHSD17B10EIF4A3 | |
| SCHEMBL19737654 | 0.81 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL19751511 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTHSD17B10FABP6 | |
| SCHEMBL26700316 | 0.75 | EIF4A3 (0.34) | MAPTEIF4A3PTGS1PTGS2 | |
| SCHEMBL13036607 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTHSD17B10EIF4A3 | |
| SCHEMBL15828687 | 0.74 | MAPT (0.36) | ALDH1A1GAAMAPTHSD17B10FABP6 | |
| SCHEMBL26005534 | 0.73 | PTGS1 (0.37) | MAPTEIF4A3PTGS1PTGS2 | |
| SCHEMBL69296 | 0.70 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTHSD17B10FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |