Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19737442 | 0.82 | ADRA2A (0.41) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL20125065 | 0.81 | ALDH1A1 (0.36) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL19751550 | 0.81 | ALDH1A1 (0.36) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL19737654 | 0.81 | ALDH1A1 (0.36) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL19737592 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL30954167 | 0.75 | FABP6 (0.41) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL15828688 | 0.74 | MAPT (0.36) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL4870090 | 0.74 | GRM1 (0.36) | MAPTALDH1A1GAAHSD17B10ADRA2A | |
| SCHEMBL12412397 | 0.73 | PTGS1 (0.37) | MAPTEIF4A3TP53SMN1; SMN2PTGS1 | |
| SCHEMBL69296 | 0.70 | ALDH1A1 (0.49) | MAPTALDH1A1GAAHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055823-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2020-02-20 | — | — | US | disclosed |
| US-20170362180-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362180-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | MAPT 4550/4885ALDH1A1 1445/4885GAA 3410/4885 |
| US-20200055823-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | MAPT 4550/4885ALDH1A1 1445/4885GAA 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.