Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17889765 | 0.85 | KDM5A (0.49) | KDM5AKDM4AKDM5BKDM4C | |
| SCHEMBL19514197 | 0.80 | KDM4E (0.39) | KDM4EATMMAOACHEK2 | |
| SCHEMBL17889766 | 0.79 | KDM5A (0.51) | KDM4EKDM5AKDM4AKDM5BKDM4C | |
| SCHEMBL20125322 | 0.67 | KDM5A (0.62) | KDM5AKDM4AKDM5BKDM4C | |
| SCHEMBL20125300 | 0.66 | KDM5B (0.64) | KDM5AKDM4AKDM5BKDM4C | |
| SCHEMBL20125337 | 0.66 | KDM5B (0.61) | KDM5AKDM4AKDM5BKDM4CPOLB | |
| SCHEMBL20125267 | 0.64 | KDM5B (0.65) | KDM5AKDM4AKDM5BKDM4CCHEK2 | |
| SCHEMBL16157309 | 0.64 | KDM5A (0.60) | KDM5AKDM4AKDM5BKDM4C | |
| SCHEMBL20125258 | 0.63 | KDM5B (0.59) | KDM5AKDM4AKDM5BKDM4C | |
| SCHEMBL20125307 | 0.63 | KDM5A (0.71) | KDM5AKDM4AKDM5BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |