Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909686 | 0.81 | KDM5A (0.45) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL29958532 | 0.72 | KMT2A (0.47) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL16157363 | 0.71 | KDM5A (1.00) | KDM5AKDM4CKDM4ERAB9AL3MBTL1 | |
| SCHEMBL29956271 | 0.70 | TRIM24 (0.49) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL9034644 | 0.69 | CCR1 (0.52) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL29957644 | 0.69 | KDM5A (0.41) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL29951570 | 0.69 | CCR1 (0.43) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL29950704 | 0.69 | CCR1 (0.43) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL13132297 | 0.69 | TRIM24 (0.51) | KDM5AKDM4CCCR1CCR5CCR8 | |
| SCHEMBL29951162 | 0.69 | PIM1 (0.48) | KDM5AKDM4CCCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968282-B1 | HISTONE DEMENTHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2018-05-09 | — | — | EP | disclosed |