Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.34 |
| ▸ | PIM1 | P11309 | 4/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909686 | 0.81 | KDM5A (0.45) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL29951570 | 0.79 | CCR1 (0.43) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL13132297 | 0.79 | TRIM24 (0.51) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL29957656 | 0.76 | ALDH1A1 (0.41) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL29951162 | 0.76 | PIM1 (0.48) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL20125333 | 0.69 | KDM5A (0.55) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL1696892 | 0.68 | KMT2A (0.55) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL29954012 | 0.68 | TRIM24 (0.64) | KMT2ATRIM24TRIM33PIM3PIM1 | |
| SCHEMBL29956273 | 0.68 | KMT2A (0.54) | CCR1CCR5CCR8KMT2ATRIM24 | |
| SCHEMBL29951398 | 0.68 | PNP (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |