SCHEMBL20125565

SCHEMBL20125565

Cc1cc(-c2ccccc2)cc(C2=CCCC=C2)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.37
MEN1 O00255 5/20 0.37
LMNA P02545 2/20 0.34
CYP19A1 P11511 1/20 0.34
RAB9A P51151 8/20 0.34
NPC1 O15118 7/20 0.34
KDM4E B2RXH2 4/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
MAPT P10636 7/20 0.33
ADORA2B P29275 2/20 0.33
ADORA1 P30542 2/20 0.33
ADORA2A P29274 1/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
NFKB1 P19838 1/20 0.33
HTT P42858 1/20 0.33
NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21338518 0.85 LMNA (0.47) KMT2AMEN1LMNARAB9ANPC1
SCHEMBL26033261 0.84 CYP19A1 (0.41) KMT2AMEN1CYP19A1RAB9AKDM4E
SCHEMBL20940398 0.81 KMT2A (0.43) KMT2AMEN1LMNARAB9AKDM4E
SCHEMBL20125555 0.81 AGTR1 (0.41) KMT2AMEN1LMNARAB9ANPC1
SCHEMBL23682198 0.81 KMT2A (0.46) KMT2AMEN1LMNARAB9AKDM4E
SCHEMBL21480691 0.80 MEN1 (0.35) KMT2AMEN1LMNACYP19A1RAB9A
SCHEMBL9218143 0.77 MEN1 (0.50) KMT2AMEN1LMNACYP19A1RAB9A
SCHEMBL15073895 0.75 KDM4E (0.49) KMT2AMEN1LMNARAB9ANPC1
SCHEMBL23181555 0.75 PIK3R1 (0.35) KMT2AMEN1CYP19A1RAB9AKDM4E
SCHEMBL316979 0.75 MEN1 (0.58) KMT2AMEN1LMNACYP19A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2675867-B1 MATERIAL FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL IND INC (KR) 2018-05-09 EP disclosed