SCHEMBL316979

SCHEMBL316979

Cc1cc(-c2ccccc2)cc(-c2ccccc2)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
MAPT P10636 4/20 0.50
ALDH1A1 P00352 4/20 0.50
ADORA1 P30542 4/20 0.50
KDM4E B2RXH2 3/20 0.50
RAB9A P51151 3/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
ADORA2B P29275 1/20 0.50
CYP19A1 P11511 1/20 0.50
NPC1 O15118 2/20 0.49
HPGD P15428 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
TSHR P16473 1/20 0.48
ATM Q13315 1/20 0.48
ADORA2A P29274 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16376443 0.98 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL18538850 0.98 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL16373472 0.98 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL30928310 0.98 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL21031240 0.94 MEN1 (0.53) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL9218143 0.93 MEN1 (0.50) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL29262260 0.92 MEN1 (0.70) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL30928306 0.92 MEN1 (0.70) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL21031241 0.92 MEN1 (0.56) MEN1KMT2AMAPTALDH1A1ADORA1
SCHEMBL13203397 0.92 MEN1 (0.51) MEN1KMT2AMAPTALDH1A1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222184-B1 PREPARATION AND USE OF GAMMA-BUTYROLACTONES AS CROSS-LINKING AGENTS DU PONT (US) 2006-11-02 EP claimed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
WO-2008044217-A2 2-AMINOCARBONYL-PYRIDINE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2008-04-17 WO disclosed
EP-1569633-A4 CA IX-SPECIFIC INHIBITORS INST VIROLOGY (SK) 2008-03-05 EP disclosed
EP-1222184-B1 PREPARATION AND USE OF GAMMA-BUTYROLACTONES AS CROSS-LINKING AGENTS DU PONT (US) 2006-11-02 EP disclosed
US-20060057068-A1 CA IX-specific inhibitors INSTITUTE OF VIROLOGY SLOVAK ACADEMY OF SCIENCES (SK) 2006-03-16 US disclosed
EP-1569633-A2 CA IX-SPECIFIC INHIBITORS INSTITUTE OF VIROLOGY (SK) 2005-09-07 EP disclosed
US-6833460-B2 Alternatives for isocyanates in coating compositions and application processes E. I. DU PONT DE NEMOURS AND COMPANY 2004-12-21 US disclosed
US-20040146955-A1 CA IX-specific inhibitors INSTITUTE OF VIROLOGY SLOVAK ACADEMY OF SCIENCES (SK) 2004-07-29 US disclosed
WO-2004048544-A2 CA IX-SPECIFIC INHIBITORS BAYER HEALTHCARE (US) 2004-06-10 WO disclosed
US-6423850-B1 CROSSLINKING COATINGS E.I. DU PONT DE NEMOURS AND COMPANY 2002-07-23 US disclosed
US-4006149-A COBALT CONTAINING STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917913-B2 Substituted oxepines OXGR1, OXTR, OCIAD2 MEN1 2568/4885KMT2A 1267/4885MAPT 1547/4885
US-20060057068-A1 CA IX-specific inhibitors CA9, CA2, CA6 MEN1 1315/4885KMT2A 1339/4885MAPT 4249/4885
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 MEN1 3319/4885KMT2A 3656/4885MAPT 758/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 MEN1 2447/4885KMT2A 3397/4885MAPT 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.