Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | PPARA | Q07869 | 15/20 | 0.49 |
| ▸ | PPARD | Q03181 | 6/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125593 | 0.91 | PPARA (0.61) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL29358494 | 0.91 | PPARA (0.61) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL3922 | 0.91 | PPARA (0.61) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL14379043 | 0.91 | PPARA (0.61) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL7462895 | 0.88 | PPARA (0.52) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL7454210 | 0.86 | PPARG (0.56) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL27360910 | 0.85 | PPARA (0.47) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL896413 | 0.85 | PPARG (0.52) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL3974261 | 0.85 | PPARG (0.55) | PPARGPPARAPPARDPSEN1PSEN2 | |
| SCHEMBL13451554 | 0.84 | PPARG (0.54) | PPARGPPARAPPARDPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846693-B1 | N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-01-23 | — | — | EP | claimed |
| CN-1069901-C | N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 2001-08-22 | — | — | CN | claimed |
| US-6030990-A | ANTIDIABETIC AND -LIPEMIC AGENTS; PARTICULARLY FOR NON-INSULIN DEPENDENT DIABETES MELLITUS, A BLOOD SUGAR-LOWERING DRUG THAT IMPROVES THE INSULIN RESISTANCE AND HAS HIGH SAFETY AND EFFICIENCY | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-02-29 | — | — | US | claimed |
| US-6001862-A | ADMINISTERING TO A PATIENT SUFFERING FROM NON-INSULIN DEPENDENT DIABETES MELLITUS A N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE COMPOUND | KYORIN PHARAMEUTICALS CO., LTD. (JP) | 1999-12-14 | — | — | US | claimed |
| CN-1186489-A | N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same | KYORIN SEIYAKU KK (JP) | 1998-07-01 | — | — | CN | claimed |
| EP-0846693-A1 | N-BENZYLDIOXOTHIAZOLIDYLBENZAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-06-10 | — | — | EP | claimed |