Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.59 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125593 | 0.91 | PPARA (0.61) | PPARAPPARDPPARGPTPN1PSEN1 | |
| SCHEMBL14379043 | 0.91 | PPARA (0.61) | PPARAPPARDPPARGPTPN1PSEN1 | |
| SCHEMBL3922 | 0.91 | PPARA (0.61) | PPARAPPARDPPARGPTPN1PSEN1 | |
| SCHEMBL29358494 | 0.91 | PPARA (0.61) | PPARAPPARDPPARGPTPN1PSEN1 | |
| SCHEMBL6236525 | 0.88 | ROCK2 (0.49) | PPARAPPARDPPARGLMNAROCK2 | |
| SCHEMBL13847879 | 0.87 | PTPN1 (0.51) | PPARAPPARGLMNAROCK2ROCK1 | |
| SCHEMBL13524847 | 0.87 | PTPN1 (0.51) | PPARAPPARGLMNAPTPN1 | |
| SCHEMBL6378335 | 0.86 | FFAR1 (0.55) | PPARAPPARGLMNASMN1; SMN2ROCK2 | |
| SCHEMBL6605626 | 0.85 | PPARA (0.56) | PPARAPPARDPPARGLMNASMN1; SMN2 | |
| SCHEMBL305177 | 0.84 | PTPN1 (0.49) | PPARAPPARDPPARGLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207158-B1 | SUBSTITUTED BENZYLTHIAZOLIDINE-2,4-DIONE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2005-05-25 | — | — | EP | claimed |