SCHEMBL20126552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29152300	0.89	HTR2C (0.53)	HTR2CHTR6CALM1IDH1SLC6A4
	SCHEMBL10707308	0.84	CALM1 (0.60)	HTR2CHTR6CALM1IDH1SLC6A4
	SCHEMBL534639	0.81	CALM1 (0.63)	HTR2CHTR6CALM1IDH1SLC6A4
	SCHEMBL920219	0.81	HTR6 (0.72)	HTR2CHTR6SLC6A4CYP1A2CYP2C9
	SCHEMBL29106534	0.81	CALM1 (0.50)	HTR2CHTR6CALM1IDH1PRSS1
	SCHEMBL1680382	0.81	HTR2C (0.61)	HTR2CHTR6SLC6A4PRSS1PRSS2
	SCHEMBL21888595	0.78	CALM1 (0.52)	HTR2CHTR6CALM1IDH1SLC6A4
	SCHEMBL9557022	0.78	HTR2C (0.56)	HTR2CHTR6SLC6A4MAOAMAOB
	SCHEMBL7613502	0.78	CALM1 (0.75)	CALM1IDH1PRSS1PRSS2PRSS3
	SCHEMBL13971231	0.78	CALM1 (0.75)	CALM1IDH1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.