Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.35 |
| ▸ | NOS1 | P29475 | 6/20 | 0.33 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461684 | 0.93 | NOS2 (0.34) | NOS2NOS1NOS3CYP3A4TSHR | |
| SCHEMBL12248560 | 0.78 | SLC1A3 (0.33) | NOS2CYP3A4TSHRBLMBHMT | |
| SCHEMBL8101166 | 0.78 | NOS2 (0.38) | NOS2NOS1NOS3CYP3A4TSHR | |
| SCHEMBL13287266 | 0.78 | NOS2 (0.38) | NOS2NOS1NOS3CYP3A4TSHR | |
| SCHEMBL14227023 | 0.78 | NOS2 (0.38) | NOS2NOS1NOS3CYP3A4TSHR | |
| SCHEMBL16659160 | 0.78 | NOS2 (0.38) | NOS2NOS1NOS3CYP3A4TSHR | |
| SCHEMBL17407546 | 0.76 | GSR (0.41) | NOS2NOS1NOS3CYP3A4TSHR | |
| SCHEMBL6130047 | 0.75 | LMNA (0.48) | BLMKDM4CKDM4APHF8KDM2A | |
| Acetic Acid SCHEMBL28487825 | 0.75 | KDM4C (0.38) | NOS2BLMKDM4CKDM4APHF8 | |
| SCHEMBL19618273 | 0.74 | NOS2 (0.36) | NOS2NOS1NOS3SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | UNIVERSITE GRENOBLE ALPES (FR) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127586-A1 | DIHYDROPYRENE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND THEIR USES | DHPS, DPYD, DHODH | NOS2 2924/4885NOS1 3472/4885NOS3 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.