Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843493 | 0.93 | KDM4E (0.50) | KDM4EMEN1KMT2AADRB2HTR1A | |
| SCHEMBL20127147 | 0.86 | KDM4E (0.57) | KDM4EMEN1KMT2AADRB2HTT | |
| SCHEMBL16948554 | 0.83 | KDM4E (0.53) | KDM4EMEN1KMT2AADRB2HTR1A | |
| SCHEMBL21843492 | 0.82 | KDM4E (0.53) | KDM4EMEN1KMT2AHTTNPSR1 | |
| SCHEMBL21480809 | 0.80 | SCN1A (0.37) | MEN1KMT2ACYP1A2 | |
| SCHEMBL16944226 | 0.79 | KDM4E (0.44) | KDM4EMEN1KMT2AADRB2HTR1A | |
| SCHEMBL25914379 | 0.76 | SCN1A (0.39) | CYP1A2 | |
| SCHEMBL14980587 | 0.76 | KMT2A (0.47) | KDM4EMEN1KMT2AADRB2ATM | |
| SCHEMBL17936208 | 0.75 | KDM4E (0.44) | KDM4EKMT2AADRB2HTR1APOLB | |
| SCHEMBL13946699 | 0.75 | HSD17B10 (0.56) | KDM4EMEN1KMT2AADRB2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10610598-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20180134843-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | UNIV VANDERBILT (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125983-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | STT3A, STT3B, B3GAT3 | KDM4E 3069/4885MEN1 2164/4885KMT2A 2891/4885 |
| US-10610598-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | STT3A, STT3B, B3GAT3 | KDM4E 3069/4885MEN1 2164/4885KMT2A 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.