SCHEMBL16948554

SCHEMBL16948554

CCOCC(O)CNCCOCCOCCNCC(O)COCC

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
ADRB2 P07550 3/20 0.39
HTR1A P08908 2/20 0.39
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
POLB P06746 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.35
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17936208 0.90 KDM4E (0.44) KDM4EADRB2HTR1AADRB1ADRB3
SCHEMBL16948555 0.86 KDM4E (0.59) KDM4EADRB2ADRB1ADRB3MEN1
SCHEMBL14198102 0.84 KDM4E (0.57) KDM4EADRB2ADRB1ADRB3KMT2A
SCHEMBL20127149 0.83 KDM4E (0.52) KDM4EADRB2HTR1AADRB1ADRB3
SCHEMBL29624902 0.83 KDM4E (0.38) KDM4EADRB2HTR1AADRB1ADRB3
SCHEMBL21843493 0.81 KDM4E (0.50) KDM4EADRB2HTR1AADRB1POLB
SCHEMBL11235646 0.81 KDM4E (0.53) KDM4EADRB2HTR1AADRB1ADRB3
SCHEMBL16944226 0.80 KDM4E (0.44) KDM4EADRB2HTR1AADRB1ADRB3
SCHEMBL17188506 0.80 KDM4E (0.48) KDM4EADRB2ADRB1ADRB3POLB
SCHEMBL9007548 0.79 KDM4E (0.83) KDM4EMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820864-B2 Aqueous polyglycidol synthesis with ultra-low branching VANDERBILT UNIVERSITY (US) 2023-11-21 US disclosed
US-9757463-B2 Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures VANDERBILT UNIVERSITY (US) 2017-09-12 US disclosed
US-9745419-B2 Aqueous polyglycidol synthesis with ultra-low branching VANDERBILT UNIVERSITY (US) 2017-08-29 US disclosed
US-20160206743-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures VANDERBILT UNIVERSITY 2016-07-21 US disclosed
US-9161983-B2 Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures VANDERBILT UNIVERSITY (US) 2015-10-20 US disclosed
US-20150210805-A1 AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING VANDERBILT UNIVERSITY 2015-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160206743-A1 Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures STT3A, STT3B, B3GAT3 KDM4E 3069/4885ADRB2 3662/4885HTR1A 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.